Technical Analyst II

University Health Network - Toronto, ON (30+ days ago)

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University Health Network (UHN) is looking for an experienced professional to fill the key role of Technical Analyst II in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN's five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

A Technical Analyst II position is available in the laboratory of Dr. Trevor Pugh, PhD, FACMG at the Princess Margaret Cancer Centre / University Health Network in Toronto, Canada. Located in the MaRS Centre in the heart of the downtown Discovery District, we are an integral component of multiple translational genomics projects and platforms including the Cancer Genomics Program, Tumour Immunotherapy Program, Princess Margaret Genomics Centre, and the Translational Genomics Laboratory, a joint initiative with the Ontario Institute for Cancer Research. While collaborating with clinicians and scientists we have embarked on a Personalized Cancer Medicine initiative—a multi-faceted, integrated approach aimed at giving the right treatment for the right patient at the right time. Due to rapid expansion, there is a need for a Technical Analyst II to work under the direction of the Senior Software Developer to:

  • Develop computational approaches to large-scale interpretation of genomic variants and novel visualization approaches to depict these data in support of clinical reporting
  • Develop automated pipelines for genomic data transformation and annotation
  • Build/maintain a catalog/inventory of the clinical and genomic datasets generated, to enable high-level browsing by clinicians and researchers
  • Develop programmatic approaches to link genomic and clinical databases within cBioPortal
  • Interact with variant interpretation/annotation teams within local clinical diagnostic laboratories to streamline the interface between interpretation and reporting into the medical record
  • Undergraduate degree in computer science, computer engineering, or a similar discipline
  • Minimum 3 years of related experience
  • Knowledge, interest, or experience in molecular biology
  • Proven development experience with relational databases (e.g., MySQL) and familiarity with the fundamental principles of data modelling and management.
  • Knowledge of multiple computer systems for database development, coding, statistics, visual design, etc.
  • Significant experience with Shell scripts, JavaScript, Python, Perl or R
  • Practical experience with version control tools (e.g. git)
  • Excellent written and verbal communication skills, excellent organization, prioritization skills, computer skills, ability to learn quickly and work independently
  • Ability to work under pressure and with attention to detail
  • Ability to perform duties in a professional and courteous manner and produce high quality work while meeting deadlines in accordance with UHN standards
For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, and possess all the required experience and qualifications should apply.