Research Asst/Tech 2 (Reid Lab)

University of British Columbia - Vancouver, BC (30+ days ago)

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Job Posting

Job ID:
38397

Location:
Vancouver - Hospital Site

Employment Group:
Technicians & Research Assists

Job Category:
Non Union Research/Technical

Classification Title:
Research Asst/Tech 2

Business Title:
Research Asst/Tech 2 (Reid Lab)

VP/Faculty:
Faculty of Medicine

Department:
Paediatrics

Salary Range:
$44,438.00 (minimum) - $48,696.00 (midpoint) - $52,955.00 (maximum)

Full/Part Time:
Full-Time

Desired Start Date:
2020/12/01

Job End Date:
2021/11/30

Funding Type:
Grant Funded

Closing Date:
2020/10/07

Available Openings:
1

Guiding principle: "Midpoint" of the hiring salary range means the individual possesses full job knowledge, qualifications and experience.

Job Summary

The BRAvE initiative at BC Children's Hospital investigates innovative approaches to precision medicine for childhood cancer patients. We conduct molecular (genetic and proteomic) analysis of patient biopsies, evaluate drug sensitivity and study patient specific model systems to better understand each child's individual cancer and devise new ways to inform treatment.

We are seeking an exceptional research technician to pursue this goal together with us and join our dynamic translational research team.

The individual's main role is to conduct routine experiments and data analysis, maintain infrastructure, and support development of new analysis pipelines. We are seeking an aspiring individual with strong analytical and organizational skills, exceptional attention to detail, expertise in nucleic acid and protein extraction, cell biology and biochemistry.

Organizational Status

The successful candidate will report to the BRAvE project manager and the BRAvE leadership team.

Work Performed

  • Conduct routine nucleic acid extraction and preparation for next generation sequencing
  • Conduct routine protein extraction and preparation for LC-MS/MS analysis
  • Perform initial analysis of genome and proteome data
  • Generate reports (quality control and performance metrics, per patient, study overviews, focused on research question)
  • Support maintenance, calibration, and operation of liquid-handlers, next generation sequencing and liquid chromatography tandem mass spectrometry instrumentation
  • Contribute to improving NGS capabilities (e.g. introduce RNA-seq, immune response panel, BCR-TCR)
  • Contribute to improving proteomic capabilities (e.g. introduce automation and develop methods and SOPs for posttranslational modifications and targeted assays)
  • Contribute to development of new analytical techniques and methodologies.
  • Contribute to culture and drug sensitivity assays of primary and xenograft expanded cells
  • Participate in meetings related to technical, scientific and organizational aspects of the project
  • Other duties as required.
Supervision Received

Works under general supervision.

Supervision Given

None

Consequence of Error/Judgement

Errors may result in the permanent loss of irreplaceable specimen, loss of thousands of dollars of material and/or damage to equipment. Loss of research results could result in the failure of a funded project and put in jeopardy any future funding and the international reputation of the Laboratory and the Institute.

Qualifications

High School graduation. Graduate degree in a relevant discipline preferred. Minimum of 2 years related experience or the equivalent combination of education and experience. All relevant UBC safety courses including biosafety and chemical safety are required but can be completed during orientation. *

  • Exceptional organizational skills and attention to detail
  • Demonstrated expertise in cell biology and biochemical research methods
  • Expertise in genomics and proteomics an asset.
  • Strong organizational skills and ability to work in a team-oriented environment.
  • Good English communication skills.
All positions in the Department of Pediatrics at BC Children's Hospital require a Criminal Record Check (CRC). A pre-employment CRC is required as part of the recruitment process and any offer of employment is contingent pending positive results of the CRC.

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Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority.